Hamburger
Fresh, hand-formed patties hot off the grill and placed on a soft, toasted sesame seed bun. Choose as many toppings as you want.
Brand Certified
Five Guys
4.5(1,050 reviews)
Certified by Five Guys • Jun 14, 2026
Business Details
5331 S. Calle Santa Cruz, Tucson, AZ
85706, United States
Certified by Five Guys • Jun 14, 2026
(520) 294-1354
Certified by Five Guys • Jun 14, 2026
https://restaurants.fiveguys.com/5331-s-calle-santa-cruz
Certified by Five Guys • Jun 14, 2026
About
Certified by Five Guys • Jun 14, 2026
Fast Food RestaurantAmerican RestaurantHot Dog RestaurantRestaurantBurger Joint
Your nearby Five Guys at 5331 S. Calle Santa Cruz in Tucson is ready to offer you a classic take on burgers, hot dogs, fries, milkshakes and more! Whether it's using fresh ground beef (there are no freezers in our restaurants), double-cooking our fries in 100 percent peanut oil, hand-preparing fresh ingredients every morning or serving peanuts while you wait, we strive to provide the best experience each and every time you visit. With more than 250,000 ways to customize your burger and 1,000+ milkshake combinations, satisfying your craving is just a click away!
Details
- Dine-inAvailable
- DeliveryAvailable
- TakeoutAvailable
- DebitAvailable
Location
Certified by Five Guys • Jun 14, 2026
Hours
Certified by Five Guys • Jun 14, 2026
Monday11:00 AM - 10:00 PM
Tuesday11:00 AM - 10:00 PM
Wednesday11:00 AM - 10:00 PM
Thursday11:00 AM - 10:00 PM
Friday11:00 AM - 10:00 PM
Saturday11:00 AM - 10:00 PM
Sunday11:00 AM - 10:00 PM
Menu
1 menu · 19 items
Explore offerings from Five Guys on 5331 S. Calle Santa Cruz in Tucson, with popular main menu available at this location.
US Menu
19 items
Main Menu
Cheeseburger
American-style cheese melted between fresh patties and placed on a soft, toasted sesame seed bun. Choose as many toppings as you want.
Bacon Burger
Hand-formed patties hot off the grill, layered with strips of crispy apple-wood smoked bacon and placed on a soft, toasted sesame seed bun. Choose as many toppings as you want.
Bacon Cheeseburger
Fresh patties hot off the grill with American- style cheese and crispy apple-wood smoked bacon. Placed on a soft, toasted sesame seed bun. Choose as many toppings as you want.
Little Hamburger
Fresh, hand-formed patty hot off the grill. Add as many toppings as you want.
Little Cheeseburger
Fresh, hand-formed patty hot off the grill with American- style cheese. Add as many toppings as you want.
Little Bacon Burger
Fresh, hand-formed patty hot off the grill with strips of crispy apple-wood smoked bacon on top. Add as many toppings as you want.
Little Bacon Cheeseburger
Fresh, hand-formed patty hot off the grill with American- style cheese and strips of crispy apple-wood smoked bacon on top. Add as many toppings as you want.
Kosher Style Hot Dog
All-beef hot dog, split and grilled lengthwise for a caramelized exterior with any of your favorite toppings.
Cheese Dog
All-beef hot dog, split and grilled lengthwise for a caramelized exterior with a layer of American- style cheese on top and any of your favorite toppings.
Bacon Dog
All-beef hot dog, split and grilled lengthwise for a caramelized exterior with a layer of apple-wood smoked bacon and any of your favorite toppings
Bacon Cheese Dog
All-beef hot dog, split and grilled lengthwise for a caramelized exterior, American-style cheese on top, a layer of apple-wood smoked bacon and any of your favorite toppings.
Veggie Sandwich
Freshly grilled onions, mushrooms and green peppers layered with lettuce and tomatoes on a soft, toasted sesame seed bun. Or start with the bun and build your own from scratch. Not a veggie burger.
Cheese Veggie Sandwich
Freshly grilled onions, mushrooms and green peppers layered with lettuce, tomatoes and slices of American style cheese on a soft, toasted sesame seed bun. Or start with the bun and cheese and build your own from scratch. Not a veggie burger.
Grilled Cheese
Slices of American style cheese melted on an inside-out sesame seed bun with toppings of your choice and grilled until golden brown.
BLT
Strips of crispy apple-wood smoked bacon from one of America’s last smokehouses, fresh tomato slices, mayo and hand-shredded lettuce on a soft, toasted sesame seed bun.
Five Guys Style
Freshly made boardwalk-style fries, cooked in pure, cholesterol-free, 100% peanut oil. Cut fresh and cooked twice – firm on the outside and mashed potato on the inside.
Cajun Style
Freshly made boardwalk-style fries, cooked in pure, cholesterol-free, 100% peanut oil, and then showered with a heavy dose of Cajun spice. Cut fresh and cooked twice – firm on the outside and mashed potato on the inside.
Milk Shake
Handspun vanilla milkshakes with or without whipped cream. Choose as many of our free mix-ins as you like.
Products & Services
1 list · 8 items
Reviews
4.5
1,050 reviews
5 stars
747
4 stars
181
3 stars
62
2 stars
23
1 star
37
- RNRobin NielsenJun 8, 20264.0Pricey but good
- EHEd HernandezApr 25, 20261.0They are awful , slow moving and to big move efficiently
- JRJuan RiveraApr 19, 20261.0I remember when coming here actually meant something—great food and even better customer service. That’s why my family and I made it a tradition to come every Sunday. We’re usually a group of 6–10, loyal customers who’ve supported this place consistently. What makes this even more disappointing is that I used to be part of that culture. When I was 18, I worked at the Campbell location. I knew Joe and the original owners, and they made it clear from day one: customer service was everything. Having a great attitude, respecting customers, and keeping a clean, sanitary environment wasn’t optional—it was the standard. Today completely changed that. We moved two tables together to sit as a family, something we’ve done many times before without issue. A staff member with short hair—who was cleaning windows and handling trash with her hands—came up to me in front of other customers and told me, in a wierd tone, to put everything back when we were done. The way it was said made me feel I was begging for food Like if they were doing me a favor. What made things worse is that shortly after handling trash, she went straight to the back to prepare food. I didn’t see any clear handwashing or glove change. That raises serious concerns about hygiene and food safety. This experience wasn’t just disappointing—it completely broke the trust I had in this place. Between the poor customer service and concerns about cleanliness, this will be the last time my family and I come here. If you’re thinking about eating here, just be aware: how a place treats its customers and handles basic hygiene matters more than anything else.
- KSKristen SanchezApr 11, 20265.0Food was great and staff were polite. They apologized for the wait even though it was a very short wait. I'll definitely come again
- PBP BodyApr 11, 20264.0Great burgers
Frequently Asked Questions About Five Guys
What is the Five Guys story/How did you guys get your name?
Five Guys began its pursuit to redefine the global burger landscape in 1986 when Jerry and Janie Murrell asked three of their sons whether they wanted to start a business or go to college. Now, three decades after our first location opened in Arlington, Va., Five Guys – a fast-casual restaurant chain named for the Murrells' five sons – serves a classic take on hamburgers, fries and milkshakes in more than 1,700 locations across 24 countries.
You can read more about the story of Five Guys at www.FiveGuys.com!
How many restaurants does Five Guys have?
As of January 2026, we have more than 1,900 locations in over 24 countries!
Does Five Guys offer delivery?
Most North American locations offer delivery. The best way to find out if the location nearest to you offers delivery is to visit our website or download the app.
Additionally, we work with all major third-party delivery companies in the U.S., including DoorDash and Uber, so feel free to search for Five Guys through their platforms!
Does Five Guys offer gluten-free options?
The only products we offer that contain gluten are our buns, hot dogs (Canada only), HP sauce (UK only), and the malt vinegar condiment for our fries. In Canada, our Poutine Gravy condiment also contains gluten. All of our sandwiches, including burgers, hot dogs and the veggie sandwich, are available without a bun via our wrap or bowls.
While our crew members do all they can to avoid it, there is always a risk of cross-contamination. Please review our nutritional, ingredient and allergen chart for the most accurate information.
Why does Five Guys have peanuts for free?
Serving peanuts for free began as a way for people to pass the time while they waited for us to cook up their meals (way back in the day, before smartphones). It was such a hit, and has become such a Five Guys tradition, that we keep our stores stocked with peanuts to this day.
What is the best way to reheat leftover fries?
Leftover fries are excellent reheated in the oven (or Air Fryer). According to Chad Murrell, one of the Five Guys, just pop them in a 350-degree oven for about 10-15 minutes.
Also, give those leftover fries a try as hash browns, home fries, or even as the filling in an omelet.
Why is Five Guys switching from a fry cup to a fry bag?
We are switching to fry bags to ensure your fries stay fresher and as part of our larger commitment to the environment. The bags allow air to circulate better, so fries stay fresh during delivery and takeout. Same portions, same great fries – just smarter packaging that’s also better for the environment.
Does Five Guys accept reservations at the Tucson Calle Santa Cruz location?
No, Five Guys at 5331 S. Calle Santa Cruz in Tucson does not accept reservations.
What are the operating hours of Five Guys in Tucson, AZ?
Five Guys at this location is open daily from 11:00 AM to 10:00 PM.
Does Five Guys offer delivery and what are the delivery hours?
Yes, Five Guys offers delivery every day from 11:00 AM to 9:30 PM. You can order online at their delivery URL.
Can I customize my burger and milkshake at Five Guys?
Yes, Five Guys offers over 250,000 ways to customize your burger and more than 1,000 milkshake combinations.
What payment methods are accepted at this Five Guys location?
They accept American Express, Android Pay, Apple Pay, Cash, Discover, Mastercard, and Visa.
Does Five Guys at this location have outdoor seating and is it wheelchair accessible?
Yes, the restaurant has outdoor seating and both the entrance and restrooms are wheelchair accessible.
Are children welcome at Five Guys in Tucson?
Yes, children are welcome at this location and the restaurant also provides high chairs.
What nearby places can I visit before or after dining at Five Guys?
Nearby you can visit Tucson Spectrum Dentistry for your dental needs or LA Fitness for a workout. There's also Red Lobster if you're looking for seafood options.
Is there a clothing store near Five Guys where I can shop?
Yes, nearby there are multiple clothing stores such as Torrid, JCPenney, Lane Bryant, and rue21 where you can shop.
How can I get to Five Guys if I'm using public transportation or visiting nearby retail areas?
You can visit nearby retail stores like Best Buy or Discount Tire and then easily walk to Five Guys located at 5331 S. Calle Santa Cruz. These nearby spots can help orient you, and the area is accessible for pedestrian visitors.
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