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Panera Bread Durham welcomes guests to our café with warm hospitality and quality ingredients. We serve a variety of menu favorites for breakfast, lunch, and dinner—including fresh coffee, bakery items, salads, soups, and sandwiches—crafted to help you feel good about what you’re enjoying. Whether you’re dining in while enjoying complimentary Wi‑Fi, ordering online for Rapid Pick‑Up, enjoying delivery, or planning catering for a large group, Panera Bread Durham is here to make your day a little better. Food as it should be.
Hope was amazing her care and professionalism was so appreciated. It was a special team during a stressful time for us. Thanks again 👍
TM
Tracey Mitchell
Jan 29, 2026
4.0
Nice little cafe inside of Duke University Medical Center. Fast service and friendly staff!
EC
Erin Clancy
Jan 17, 2026
2.0
Panera’s decline is so sad. I ordered a bagel with cream cheese. I was handed an underbaked lump of carbs masquerading as a bagel. I asked for another one, and I was given an underbaked lump of carbs they ran through a toaster. I blame private equity, not the staff.
DS
Diane S
Oct 20, 2025
1.0
Staff is not friendly. Got over charged for sandwich. Got charged for a big bowl of chili when they only gave me half the amount. A TOTAL RIP OFF
TM
Tori morgan
Mar 18, 2025
5.0
Staff is always friendly and relatable. Food is absolutely delicious. The pomegranate drink tastes wonderful if you add a little sugar 😉. Also, I can tell they work very hard, it shows in how they work together as a team. 10/10 would recommend.
Does Panera Bread at 10 Duke Medicine Circle accept reservations?
No, this Panera Bread location does not accept reservations.
What types of meals are served at Panera Bread in Durham?
They serve breakfast, lunch, brunch, and dinner.
What are the opening hours for Panera Bread during the weekdays?
Panera Bread is open from 6:00 AM to 8:00 PM Monday through Friday.
Is delivery available at the Panera Bread on Duke Medicine Circle?
No, this location does not offer delivery services.
Can I use Rapid Pick-Up or order online for quick service at this Panera Bread?
Yes, you can order online using Rapid Pick-Up to grab your order quickly.
What types of payment does Panera Bread accept?
They accept American Express, Cash, Discover, MasterCard, and Visa.
Is there drive-thru or curbside pickup available at this Panera Bread?
No, this location does not have a drive-thru or curbside pickup.
What are some nearby medical facilities around Panera Bread at 10 Duke Medicine Circle?
Nearby medical facilities include Duke Medicine Pavilion, Duke Health, Duke Emergency Department, and Duke Cancer Center, which makes it convenient for visitors or staff to grab meals before or after appointments.
Are there nearby cafes or restaurants to Panera Bread in Durham for a variety of dining options?
Yes, Tropical Smoothie Cafe is nearby, offering smoothie and café options. Visitors can enjoy different dining choices in the area.
How can the nearby Duke Medicine Pavilion Imaging and Cardiac Diagnostic units be helpful when visiting Panera Bread?
These nearby diagnostic centers are convenient for patients and staff to visit Panera Bread for meals or coffee during their appointments or workday.
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