Brand Certified
Five Guys
4.4(905 reviews)
Certified by Five Guys • Apr 12, 2026
Business Details
4222 NW 16th Blvd, Gainesville, FL
32605, United States
Certified by Five Guys • Apr 12, 2026
(352) 264-7790
Certified by Five Guys • Apr 12, 2026
https://restaurants.fiveguys.com/4222-nw-16th-blvd
Certified by Five Guys • Apr 12, 2026
About
Certified by Five Guys • Apr 12, 2026
Fast Food RestaurantAmerican RestaurantHot Dog RestaurantRestaurantBurger Joint
Your nearby Five Guys at 4222 NW 16th Blvd in Gainesville is ready to offer you a classic take on burgers, hot dogs, fries, milkshakes and more! Whether it's using fresh ground beef (there are no freezers in our restaurants), double-cooking our fries in 100 percent peanut oil, hand-preparing fresh ingredients every morning or serving peanuts while you wait, we strive to provide the best experience each and every time you visit. With more than 250,000 ways to customize your burger and 1,000+ milkshake combinations, satisfying your craving is just a click away!
Details
- Dine-inAvailable
- DeliveryAvailable
- TakeoutAvailable
- DebitAvailable
Location
Certified by Five Guys • Apr 12, 2026
Hours
Certified by Five Guys • Apr 12, 2026
Monday10:00 AM - 10:00 PM
Tuesday10:00 AM - 10:00 PM
Wednesday10:00 AM - 10:00 PM
Thursday10:00 AM - 11:00 PM
Friday10:00 AM - 11:00 PM
Saturday10:00 AM - 11:00 PM
Sunday10:00 AM - 10:00 PM
Reviews
4.4
905 reviews
5 stars
575
4 stars
196
3 stars
70
2 stars
35
1 star
29
- MSMonika SmithMar 26, 20265.0Amazing staff food quality and customer service!!!!
- SJStephen JacksonMar 25, 20265.0Best hamburgers in town. Fast service. The French fries are great.
- SHSteff HollingsworthMar 11, 20265.0Burgers and fries are really good, just quite expensive.
- JGJoyce GossMar 2, 20265.0Great
- DRDavid RichardsonFeb 27, 20265.0I've been here several times. Each time the team has been polite. On my last visit, Jess was awesome and helpful.
Frequently Asked Questions About Five Guys
What is the Five Guys story/How did you guys get your name?
Five Guys began its pursuit to redefine the global burger landscape in 1986 when Jerry and Janie Murrell asked three of their sons whether they wanted to start a business or go to college. Now, three decades after our first location opened in Arlington, Va., Five Guys – a fast-casual restaurant chain named for the Murrells' five sons – serves a classic take on hamburgers, fries and milkshakes in more than 1,700 locations across 24 countries.
You can read more about the story of Five Guys at www.FiveGuys.com!
How many restaurants does Five Guys have?
As of January 2026, we have more than 1,900 locations in over 24 countries!
Does Five Guys offer delivery?
Most North American locations offer delivery. The best way to find out if the location nearest to you offers delivery is to visit our website or download the app.
Additionally, we work with all major third-party delivery companies in the U.S., including DoorDash and Uber, so feel free to search for Five Guys through their platforms!
Does Five Guys offer gluten-free options?
The only products we offer that contain gluten are our buns, hot dogs (Canada only), HP sauce (UK only), and the malt vinegar condiment for our fries. In Canada, our Poutine Gravy condiment also contains gluten. All of our sandwiches, including burgers, hot dogs and the veggie sandwich, are available without a bun via our wrap or bowls.
While our crew members do all they can to avoid it, there is always a risk of cross-contamination. Please review our nutritional, ingredient and allergen chart for the most accurate information.
Why does Five Guys have peanuts for free?
Serving peanuts for free began as a way for people to pass the time while they waited for us to cook up their meals (way back in the day, before smartphones). It was such a hit, and has become such a Five Guys tradition, that we keep our stores stocked with peanuts to this day.
What is the best way to reheat leftover fries?
Leftover fries are excellent reheated in the oven (or Air Fryer). According to Chad Murrell, one of the Five Guys, just pop them in a 350-degree oven for about 10-15 minutes.
Also, give those leftover fries a try as hash browns, home fries, or even as the filling in an omelet.
Why is Five Guys switching from a fry cup to a fry bag?
We are switching to fry bags to ensure your fries stay fresher and as part of our larger commitment to the environment. The bags allow air to circulate better, so fries stay fresh during delivery and takeout. Same portions, same great fries – just smarter packaging that’s also better for the environment.
Does Five Guys at 4222 NW 16th Blvd accept reservations?
No, Five Guys does not accept reservations at this location.
What are the operating hours for Five Guys in Gainesville?
Five Guys is open daily from 11:00 AM to 10:00 PM.
Does Five Guys offer delivery and what are the delivery hours?
Yes, delivery is available daily from 11:00 AM to 9:30 PM. You can order online at https://order.fiveguys.com/location/millhopper/menu.
Can I place an order for pickup at Five Guys Gainesville?
Yes, Five Guys offers in-store pickup service at this location.
What types of payment does Five Guys in Gainesville accept?
They accept American Express, Android Pay, Apple Pay, Cash, Discover, Mastercard, and Visa.
What menu specialties does Five Guys offer at this location?
The specialties include hamburgers, cheeseburgers, fries, milkshakes, boardwalk fries, shakes, hot dogs, lettuce wrap, veggie sandwich, and grilled cheese.
Is the Five Guys restaurant at 4222 NW 16th Blvd family-friendly and accessible?
Yes, the restaurant welcomes children, has high chairs, a wheelchair accessible entrance and restroom.
What nearby food options can I explore before or after visiting Five Guys?
Nearby you can find Papa Johns Pizza for pizza lovers and The Flying Biscuit Cafe or Flying Biscuit Café, both offering American and southern style food and café options.
Where can I find health and wellness services close to Five Guys in Gainesville?
Nearby options include APEX Gainesville and APEX | High-Intensity Pilates for fitness, as well as several dental offices like Lozano Dental Care and Gainesville Dentistry Co.
Are there other shopping and specialty stores near Five Guys at 4222 NW 16th Blvd?
Yes, nearby are shopping options like etc boutique for women's clothing, Thornebrook Gallery for art and framing, and Crevasse's Florist of Gainesville for flowers and gifts.
Brand Certified Facts from Five Guys
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