Fast Food RestaurantAmerican RestaurantHot Dog RestaurantRestaurantBurger Joint
Your nearby Five Guys at 4222 NW 16th Blvd in Gainesville is ready to offer you a classic take on burgers, hot dogs, fries, milkshakes and more! Whether it's using fresh ground beef (there are no freezers in our restaurants), double-cooking our fries in 100 percent peanut oil, hand-preparing fresh ingredients every morning or serving peanuts while you wait, we strive to provide the best experience each and every time you visit. With more than 250,000 ways to customize your burger and 1,000+ milkshake combinations, satisfying your craving is just a click away!
Many customers feel that the prices are excessively high for the quality and quantity of food received.
Food Quality
While some reviews praise the burgers and fries as delicious and fresh, others report issues with soggy or poorly prepared items.
Service
Customer service is generally noted as friendly and efficient, although there are instances of order mistakes and lack of attentiveness.
Cleanliness
The restaurant is often described as clean, but some customers have mentioned issues with finding clean tables.
Portion Sizes
Customers appreciate the generous portions of fries, but some feel that the overall value for the price is lacking.
DL
daniela guerrero llosa
Oct 26, 2025
1.0
I’m honestly furious. We just dropped $70 at this Five Guys and asked for one simple thing: a burger with NO cheese. Instead, they completely ignored that and slapped cheese on it anyway. It’s ridiculous to spend that kind of money and have the order messed up because someone couldn’t pay attention. This kind of carelessness is exactly why I won’t be coming back… useless people
JE
J Elli
Oct 11, 2025
2.0
Disappointed two burgers and a small fry came to $40! Food was decent but way over priced.
LR
Laken Riess
Oct 5, 2025
5.0
Great place to eat
CC
CommandCookie
Sep 11, 2025
5.0
Went to 5 guys today, but only 2 guys work there.
RB
Robert Baker
Aug 5, 2025
3.0
Food is good but cost about double what it should.
What is the Five Guys story/How did you guys get your name?
Five Guys began its pursuit to redefine the global burger landscape in 1986 when Jerry and Janie Murrell asked three of their sons whether they wanted to start a business or go to college. Now, three decades after our first location opened in Arlington, Va., Five Guys – a fast-casual restaurant chain named for the Murrells' five sons – serves a classic take on hamburgers, fries and milkshakes in more than 1,700 locations across 24 countries.
You can read more about the story of Five Guys at www.FiveGuys.com!
Does Five Guys offer delivery?
As of June 2024, we have more than 1,800 locations in over 24 countries! Most of our restaurants are in the United States.
How many restaurants does Five Guys have?
As of June 2024, we have more than 1,800 locations in over 24 countries! Most of our restaurants are in the United States.
Does Five Guys offer gluten-free options?
The only products we offer that contain gluten are our buns, hot dogs (Canada only), HP sauce (UK only), and the malt vinegar condiment for our fries. In Canada, our Poutine Gravy condiment also contains gluten. All of our sandwiches, including burgers, hot dogs and the veggie sandwich, are available without a bun via our wrap or bowls.
While our crew members do all they can to avoid it, there is always a risk of cross-contamination. Please review our nutritional, ingredient and allergen chart for the most accurate information.
Is the Five Guys veggie sandwich a veggie patty?
Our veggie sandwich is not a veggie burger, but truthfully, it can be a mix of whatever you'd like. Choose any combination of our condiments and add cheese for an additional cost.
Our standard veggie is a mix of peppers, onions and mushrooms with or without cheese.
What is the best way to reheat leftover fries?
Leftover fries are excellent reheated in the oven (or Air Fryer). According to Chad Murrell, one of the Five Guys, just pop them in a 350-degree oven for about 10-15 minutes.
Also, give those leftover fries a try as hash browns, home fries, or even as the filling in an omelet.
Does Five Guys at 4222 NW 16th Blvd accept reservations?
No, Five Guys does not accept reservations at this location.
What are the operating hours for Five Guys in Gainesville?
Five Guys is open daily from 11:00 AM to 10:00 PM.
Does Five Guys offer delivery and what are the delivery hours?
Yes, delivery is available daily from 11:00 AM to 9:30 PM. You can order online at https://order.fiveguys.com/location/millhopper/menu.
Can I place an order for pickup at Five Guys Gainesville?
Yes, Five Guys offers in-store pickup service at this location.
What types of payment does Five Guys in Gainesville accept?
They accept American Express, Android Pay, Apple Pay, Cash, Discover, Mastercard, and Visa.
What menu specialties does Five Guys offer at this location?
The specialties include hamburgers, cheeseburgers, fries, milkshakes, boardwalk fries, shakes, hot dogs, lettuce wrap, veggie sandwich, and grilled cheese.
Is the Five Guys restaurant at 4222 NW 16th Blvd family-friendly and accessible?
Yes, the restaurant welcomes children, has high chairs, a wheelchair accessible entrance and restroom.
What nearby food options can I explore before or after visiting Five Guys?
Nearby you can find Papa Johns Pizza for pizza lovers and The Flying Biscuit Cafe or Flying Biscuit Café, both offering American and southern style food and café options.
Where can I find health and wellness services close to Five Guys in Gainesville?
Nearby options include APEX Gainesville and APEX | High-Intensity Pilates for fitness, as well as several dental offices like Lozano Dental Care and Gainesville Dentistry Co.
Are there other shopping and specialty stores near Five Guys at 4222 NW 16th Blvd?
Yes, nearby are shopping options like etc boutique for women's clothing, Thornebrook Gallery for art and framing, and Crevasse's Florist of Gainesville for flowers and gifts.