Need a rental car in San Diego, CA? Enterprise Rent-A-Car is Here For It. Whether your car is in the shop, you're running errands, or planning a weekend getaway, we're ready with a wide range of vehicles and flexible rental options. Enjoy easy, stress-free rentals and friendly service that gets you on your way fast. Reserve your rental car with Enterprise at our Mission Valley location today.
Took them 40 minutes to get me a car with no line and I was late for work. Returning the car was also a whole process. Will not be returning to this branch.
MG
M Guerrero
Jun 14, 2026
5.0
My favorite team to see when renting a vehicle in Enterprise in mission valley. Thanks Evie and team.
CR
Cecilia Brooke Nyholm Ramiez
Jun 13, 2026
1.0
1333 Camino del Rio S #101, San Diego, CA 92108
The staff at this location have always been friendly and courteous, which I appreciate. Unfortunately, my recent experiences have been disappointing due to ongoing operational and vehicle maintenance issues.
It has become common to wait several hours beyond my reserved pickup time because no vehicles are available at the location despite confirmed reservations. On multiple occasions, the vehicles I was eventually given had dashboard warning lights illuminated or displayed maintenance-needed notifications.
When I raised these concerns, I was told that the warning lights were "normal" and that maintenance had been completed but the codes had not been reset. As a customer, I find it difficult to accept that warning lights and maintenance alerts on rental vehicles should be considered normal.
I also brought these issues to the manager's attention, including the lengthy wait time and the vehicle condition concerns. The only compensation offered was a handwritten note on a business card for 12% off a future rental, which did not feel proportional to the inconvenience experienced.
This location used to be my preferred place to rent from, but the repeated lack of vehicle availability, extended wait times, and ongoing concerns about vehicle maintenance have significantly diminished my confidence. While I genuinely appreciate the professionalism of the staff, I am unlikely to rent from this location again unless these issues are addressed.
I took photos of the the vehicles dash boards with maintenance needed notifications as they continued to say its "normal " and "we just have to go on in and clear out codes"... since they have no vehicles on the lot to begin with, does that mean Enterprise policy is to clear out maintenance codes without maintenance? Or is it policy to provide poor customer service with un serviced vehicles and only offer 12% off next rental to those that point it out in hopes of repeat bussines?
To top it off, after I pointed out all my concerns and un satisfactory experience, the staff referred me to their car sales department, as if I would want to purchase one of their un maintained vehicles?
EW
Ernest WESTMAN
Jun 9, 2026
5.0
I had a very positive experience renting a vehicle from Enterprise. I was treated very well by an employee named Eveen. She was very patient and respectful. After 2 failed attempts at trying vehicles, she successfully directed me to a third vehicle that worked out very well for me. If I ever need to rent a vehicle again, I will be heading down to Enterprise in Mission Valley.
TS
T. Shaw
Jun 7, 2026
5.0
Busy location, staff is doing a great job and stayed helpful and friendly thru the whole transaction.
Frequently Asked Questions About Enterprise Rent-A-Car
What types of vehicles can I rent at Enterprise Rent-A-Car in San Diego?
Enterprise Rent-A-Car offers a wide range of vehicles including cars, vans, luxury cars, and trucks tailored to meet your rental needs.
Where is the Enterprise Rent-A-Car location in San Diego?
The Enterprise Rent-A-Car location is at 1333 Camino Del Rio South, #101, San Diego, CA 92108.
What are the operating hours for Enterprise Rent-A-Car in Mission Valley?
Enterprise Rent-A-Car is open Monday to Friday from 8:00 AM to 6:00 PM, Saturday from 9:00 AM to 2:00 PM, and closed on Sundays.
How can I make a reservation at the Mission Valley Enterprise Rent-A-Car?
Reservations can be made online through their website at https://www.enterprise.com/en/car-rental-locations/us/ca/san-diego-mission-valley-3245.html or by calling +1 619-260-1505.
What payment options are accepted at Enterprise Rent-A-Car in San Diego?
They accept American Express, Cash, Check, Discover, Mastercard, and Visa payment methods.
Does Enterprise Rent-A-Car offer discounts for active military members?
Yes, Enterprise Rent-A-Car provides discounts for active military personnel.
Can I get an airport pick-up service at the Mission Valley Enterprise location?
Yes, airport pick-up service is among the services offered at this Enterprise Rent-A-Car location.
Which fitness centers are located near Enterprise Rent-A-Car in Mission Valley?
Nearby fitness centers include Catalyst Physical Therapy and Wellness, Feel Good Fitness, and Chuze Fitness, which customers can visit before or after renting a vehicle.
Are there any health and wellness centers near Enterprise Rent-A-Car in San Diego?
Yes, there are several health and wellness centers nearby including SmileCare (dentist and orthodontist), Deluxe Spa Services, and Planned Parenthood Mission Valley Express Center.
What entertainment or shopping options are available close to Enterprise Rent-A-Car in Mission Valley?
Nearby options include Club Fuego dance club, 5.11 Tactical for outdoor gear and clothing, and Bridal & Veil Bridal Shop for formal wear and retail shopping.
Brand Certified Facts from Enterprise Rent-A-Car
This information is certified by Enterprise Rent-A-Car and published from the brand's official system of record. Data is distributed through an enterprise-grade knowledge management platform. Learn more about our data sources
Certified July 05, 2026Yext Knowledge Graph
Address
Categories
Geo coordinates
Legal business name
Hours of operation
Phone number
Official website
Syndication Network
Approved business data is pushed to 100+ publishers, including: