Hampton Inn & Suites St. Louis/South I-55 is Conveniently Located at I-55 & I-270 Interchange; 15 Minutes from Downtown St. Louis & The Gateway Arch. I-270 is The Major Beltway Around The City and Provides Quick Access to Illinois, West County, I-44, I-70, I-64/40 and Easy Driving to St. Louis’ Lambert Intl Airport. Each Of Our Beautifully Appointed Guest Rooms Are Non-Smoking and Feature All of The Conveniences Suited to The Savvy Business Traveler, Along With a Great Location and Recreational Amenities to Please Leisure Guests. Spacious Contemporary Guestrooms and Suites Boast a Long List of Guest Amenities Including: o
The staff received high praise for being friendly, accommodating, and attentive to guests' needs.
Cleanliness
Most reviews highlighted the hotel as exceptionally clean, with well-maintained rooms and common areas.
Breakfast Quality
Guests appreciated the breakfast variety and quality, with some noting special touches like cookies and milk in the evenings.
Noise Issues
Several customers reported issues with noise from other rooms and floors, indicating thin walls and creaky floors.
Location
The hotel is conveniently located near major routes and attractions, making it a favorable choice for travelers.
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Megan Marsh
Dec 14, 2025
4.0
Stayed here for two nights in late-November/early-December. The front desk staff was very accommodating, helpful, and insightful in the local area, area weather, and places to go and see that might not be on a touristy map.
We got snowed out all the activities while my family was there, but the hotel had good snow removal, and handling of the water/melting snow that is inevitably tracked in on shoes and outerwear.
The fitness facility is a PROPER hotel fitness facility: 2 treadmills, 1 elliptical, 1 bike, water, towels, full set of dumbbells (up to 75lbs), a 24in foam box, some kettlebells, all of which I used. The equipment was in good working order, nothing broken, chipped, cracked, or unresponsive - though I did not try the headphone jacks on the cardio machines.
The evening's milk and cookies were a nice non-pressured social event, with warm cookies (that did not taste like sugar), and whole milk available. Guests and staff mingled casually, some guests were in their pajamas as we watched the snow storm come in on the lobby TV.
Location was good too, right next to
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Lana Soto
Nov 21, 2025
5.0
This is an excellent hotel, and I am picky. It smelled SO CLEAN!! Great breakfast and wonderful kind service.
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Mike Nissly
Nov 16, 2025
5.0
As a wheelchair user the accessible room with RI shower was nearly perfect. It covered all our needs. Spacious with plenty of room to maneuver 2chairs. Bathroom setup was great! I could wheel under the sink, the stool had plenty of room around it and the shower had space. The room transitions were smooth, no lips. Overall a very nice stay. We felt refreshed. Oh, and the bed height was good.
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Anthony
Oct 30, 2025
5.0
Extremely nice staff here, the room was super clean and quiet.
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Jann Knighten
Oct 10, 2025
5.0
I often stay at hotels around the country, including very high-end hotels. I have never stayed at any hotel where the staff and customer service were so exceptional. The staff was helpful and caring from the moment I checked in and throughout my two-day stay. The food was excellent, the room immaculate, and the staff went out of their way to make sure I was comfortable. If every hotel were managed and had the excellent staff this hotel has, it would always be a pleasure to travel. I HIGHLY recommend this hotel regardless of which area of St. Louis you happen to be working or visiting.
Frequently Asked Questions About Hampton Inn & Suites St. Louis/South I-55
What accessibility features does Hampton Inn & Suites St. Louis/South I-55 offer?
The hotel offers accessible parking and an accessible elevator to accommodate guests with mobility needs.
Is parking available at Hampton Inn & Suites St. Louis/South I-55?
Yes, free self-parking is available for guests at the hotel.
Does Hampton Inn & Suites St. Louis/South I-55 allow pets?
Yes, both cats and dogs are welcome at this pet-friendly hotel.
What are the check-in and check-out times at the hotel?
Check-in time is at 3:00 PM, and check-out time is at 11:00 AM.
Is breakfast included when staying at Hampton Inn & Suites St. Louis/South I-55?
Yes, a complimentary buffet breakfast is available to guests.
Are there fitness facilities available at Hampton Inn & Suites St. Louis/South I-55?
Yes, there is a free fitness center on-site featuring equipment like treadmills and elliptical machines.
What swimming pools are available at the hotel?
The hotel features one indoor pool and a hot tub for guest use.
Can guests use digital keys at Hampton Inn & Suites St. Louis/South I-55?
Yes, digital guest room keys are available for convenient room access.
What nearby medical facilities are accessible from Hampton Inn & Suites St. Louis/South I-55?
Guests have easy access to several nearby medical centers including Mercy Family Physicians and Mercy Clinic OB/Gyn - Butler Hill for health care needs.
Are there nearby places to eat or grab a quick meal around Hampton Inn & Suites St. Louis/South I-55?
Yes, Popeyes® Louisiana Kitchen is located nearby for guests seeking fast food options during their stay.
How can guests access fitness options near Hampton Inn & Suites St. Louis/South I-55?
In addition to the hotel's fitness center, the Hampton Inn Fitness Center nearby provides additional gym facilities for guests.